Isotopically Labeled Compounds
Medchemexpress LLC Telmisartan-d3 | 1189889-44-8 | >99.7% | 517.64 | 1 MG
Telmisartan-d3 is a deuterium-labeled version of Telmisartan, a potent and long-lasting antagonist of the angiotensin II type 1 receptor (AT1). It selectively inhibits the binding of 125I-AngII to AT1 receptors with an IC50 of 9.2 nM.
- Intended for research use only
- Can be utilized as a tracer or internal standard
- Suitable for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS
- Deuteration influences pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Bis-Tris-d19 | 352534-93-1 | 99% | 50 MG
Bis-Tris-d19 is the deuterium-labeled form of Bis-Tris, a commonly used buffer. Deuteration, which involves incorporating stable heavy isotopes into drug molecules, is used as tracers for quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs. This compound is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC dGTP-d14 dilithium (2'-Deoxyguanosine-5'-triphosphate-d14 dilithium) | 2564-35-4 | 98.5% | 533.13 | 1 MG
dGTP-d14 (2'-Deoxyguanosine-5'-triphosphate-d14) dilithium is deuterium labeled dGTP. It is a guanosine nucleotide that can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides are highly susceptible to oxidative damage to 8-oxo-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Uridine-d2-1 | 40632-21-1 | 98.5% | 5 MG
Uridine-d2-1 is the deuterium labeled Uridine. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled uridine
- Used as a tracer for quantitation during drug development
- Can be used as an internal standard for quantitative analysis
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Palmitic acid-d31 | 39756-30-4 | 287.62 | 50 MG
Palmitic acid-d31 is the deuterium-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Palmitic acid-13C2 | 86683-25-2 | 258.41 | 100 MG
Palmitic acid-13C2 is a 13C-labeled long-chain saturated fatty acid commonly found in animals and plants. It can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells. This product can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Tracer for metabolic studies
- Internal standard for quantitative analysis
- Induces expression of GRP78 and CHOP in mouse granulosa cells
Medchemexpress LLC Palmitic acid-d31 sodium | 467235-83-2 | 309.60 | 50 MG
Palmitic acid-d31 (sodium) is a deuterium-labeled palmitic acid primarily used for research purposes. This compound, featuring stable heavy isotopes, acts as a tracer and an internal standard in quantitative analysis methods. Deuteration is known for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Palmitic acid-13C | 287100-87-2 | 257.42 | 50 MG
Palmitic acid-13C is the 13C-labeled version of Palmitic acid. This long-chain saturated fatty acid is found in both animals and plants and can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Mifepristone-d3 | 1228097-18-4 | 97.7% | 432.61 | 1 MG
Mifepristone-d3 is the deuterium labeled Mifepristone. It acts as a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled compound
- Acts as a progesterone receptor antagonist
- Acts as a glucocorticoid receptor antagonist
- Useful as a tracer in drug development processes
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC L-Tyrosine-2,3,5,6-d4 | 62595-14-6 | 185.21 | 25 MG
L-Tyrosine-d4 is a deuterium-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid known to inhibit citrate synthase activity in the posterior cortex.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Deoxycholic acid | 83-44-3 | 392.57 | 1 G
Deoxycholic acid, also known as cholanoic acid, is a bile acid produced as a by-product of intestinal metabolism. It acts by activating the G protein-coupled bile acid receptor TGR5. This product is intended for research use only.
- By-product of intestinal metabolism
- Activates G protein-coupled bile acid receptor TGR5
- Solid appearance, white to off-white
- High purity (99.94%)
- For research use only
Medchemexpress LLC L-Citrulline-d7 | 2483831-24-7 | 182.23 | 5 MG
L-Citrulline-d7 is the deuterium-labeled form of L-Citrulline. L-Citrulline is an amino acid that originates from ornithine during the catabolism of proline or glutamine and glutamate, or from L-arginine through the arginine-citrulline pathway. This product is intended for research use only and is not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Purity: 99.83%.
Medchemexpress LLC Veratrole-d6 | 24658-24-0 | 98.7% | 5 MG
Veratrole-d6 is a deuterium-labeled form of Veratrole (1,2-Dimethoxybenzene), a compound found in plants that attracts pollinators. Its release exhibits a circadian rhythm, playing a role in plant reproduction, species differentiation, and interactions with pollinators. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs, making labeled compounds like Veratrole-d6 valuable as tracers in drug development and research.
- Useful as a tracer in drug development
- Deuterium-labeled compound
- Supports research into pharmacokinetics and metabolic profiles
Medchemexpress LLC D-Arabinose-1-C-d | 77583-92-7 | 50 MG
D-Arabinose-1-C-d is a deuterium-labeled form of arabinose, an endogenous metabolite. This compound is intended for research use only.
- Used as a tracer in various studies.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to influence pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Piperacillin-d5 | 59702-31-7 | 98.2% | 100 UG
Piperacillin-d5 is a deuterium-labeled version of Piperacillin, a semisynthetic penicillin with broad-spectrum activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. It demonstrates greater activity against β-lactamase-producing organisms compared to other penicillins.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Appearance: solid, white to off-white.
- Molecular weight: 522.59.
- Chemical formula: C23H22D5N5O7S.